Next NIH sponsored Joint CryoEM Service Centers Webinar Series

12pm (Eastern Time)

 

Sessions start 12:00 pm GMT+1 (British Summer Time)

Event Outline

• A two-day academic symposium including prestigious talks and poster sessions
• Nobel Prize winner Richard Henderson will give the plenary public lecture “Zooming in on the molecules of life”.

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The conference aims to provide a forum to highlight state of the art developments in computational cryoEM and related themes as well as showcasing outstanding recent biological applications. We aim to promote an inclusive, friendly atmosphere welcoming both old and new to the community. Topics include instrument technology, sample preparation, image processing, single particle reconstruction, tomography and model building.
 

The schedule will also include the Diamond Light Source biological cryo-imaging user meeting for eBIC & B24.

To be held in person at Simons Electron Microscopy Center New York Structural Biology Center, New York, NY

The workshop can accommodate a total of 25 participants.
 

Apply to participate at: 

https://www.surveymonkey.com/r/RGDHFK7
 
 

The application deadline is 1 March, 2022. A final selection of participants will be made by 15 March 2022.

 For other inquiries send email to: cpotter@nysbc.org

This is the 4th of a series of practical hands-on workshops and is 
aimed at PhDs, PostDocs and scientists new to the field of single 
particle cryo-EM. During the course, participants will learn theoretical 
and practical aspects of sample preparation for single particle cryo-EM 
including prior quality control by negative staining.

There is no registration fee and meals and accommodation during the 
workshop will be provided free of charge. However, participants are 
expected to arrange and pay for their own travel to/from Grenoble. A 
maximum of 12 participants will be selected and we will accept a limited 
number of participants' samples to be tested during the workshop.

 

Speakers include Jacques Dubochet, Joachim Frank and Richard Henderson
See flyer:Â 

http://mail.ncmir.ucsd.edu/pipermail/3dem/attachments/20211220/39602e18/attachment.png

Our list of speakers includes David DeRosier, Frederick Sigworth, Tom Goddard, Steven Ludtke, Dimitry Tegunov.
 

Organizer: Wah Chiu, Stanford University

8:00-9:30 AM (PST)

Prof. David Veesler
Associate Professor at University of Washington
Talk Title: Structure-guided Coronavirus Vaccine Design
Dr. David Veesler is an associate professor of biochemistry and co-director of the Arnold & Mabel Beckman Center for Cryo-Electron Microscopy at the University of Washington. He is also a Howard Hughes Medical Institute Investigator.

Prof. Xiaoqing Pan
Professor at University of California, Irvine
Talk Title: Real Space Charge Density Mapping of Single Defects by 4D STEM
Dr. Xiaoqing Pan is a Henry Samueli Endowed Chair in Engineering and professor of materials science and engineering and physics and astronomy at University of California, Irvine. He is also the director of the Irvine Materials Research Institute and the Center for Complex and Active Materials, funded by the National Science Foundation's Materials Research Science and Engineering Centers program.

 

This workshop targets an advanced audience with pre-existing knowledge in electron tomography, data processing and/or cryo-TEM but the initial days offer an opportunity for less experienced participants to catch-up. It is planned to cover

Specimen preparation techniques for cryo-electron tomography
Cryo-CLEM
Low-dose data collection with SerialEM
Direct detectors
Cryo-STEM tomography
Processing of low-dose tilt series with IMOD
Modelling and interpretation of cryo-electron tomography data
Subtomogram averaging with PEET and other software
New approaches to cryo-ET image processing

Prospective instructors include

Florian Faessler, Institute of Science and Technology, Klosterneuburg, Austria
Helmut Gnaegi, Diatome, Switzerland
Wim Hagen, EMBL Heidelberg
Thomas Heuser, Vienna Biocenter Core Facilities, Vienna, Austria
David Mastronarde, University of Colorado, Boulder, United States
Guenter Resch, Nexperion - Solutions for Electron Microscopy, Vienna, Austria
Christiane Riedel, University of Veterinary Medicine Vienna, Austria
Florian Schur, Institute of Science and Technology, Klosterneuburg, Austria
Sharon Grayer Wolf, Weizmann Institute of Science, Rehovot, Israel
Bettina Zens, Institute of Science and Technology, Klosterneuburg, Austria

Planned to be held in person only.

The goal of this series of meetings is for technical discussions of state of the art image analysis approaches and algorithm developments to tackle challenging biological problems and to identify current limitations in the field. We have recruited an outstanding panel of speakers with topics at the 2022 meeting to include: tomography and high resolution subtomogram averaging, conformational variability, deep learning, model based refinement and automation. In addition, there will be a dedicated session for selected poster talks. All sessions will focus on interactive discussions with plenty of time for questions.

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All timings are in IST
If we are unable to accommodate you on live session, there will be

a link sent to you for lecture videos on demand after the meeting.

 

Determining structural mechanisms of allosteric regulation in ABCC family transporters using a remote cryo-EM pipeline
 

December 9th, 2021 at 12pm (Eastern Time)
 

Registration is at no-cost, but sign-up is required

Determining structural mechanisms of allosteric regulation in ABCC family transporters using a remote cryo-EM pipeline
 

December 9th, 2021 at 12pm (Eastern Time)
 

Registration is at no-cost, but sign-up is required

9 a.m. PST | 12 p.m. EST | 6 p.m. CET
 

In this GEN webinar, our expert panelists will discuss the most recent data on how cryo-EM-enabled structural insights are guiding the development of novel strategies for rational drug design in serotonin (3A) receptors and glycine receptors.

A live Q&A session will follow the presentation, offering you the chance to ask questions and engages with our panelists.

 

The 6th Microscopy Characterisation of Organicâ€"Inorganic Interfaces (MCOII) meeting will again be hosted virtually, but it will keep the main goals and aspirations of all the previous editions.  We will use the advantages of the virtual format and this time not only connect experts from different branches of the microscopy community (the life sciences and materials science) but also bridge two continents in a joint discussion on the challenging but increasingly important topic of studying hybrid organicâ€"inorganic materials.

The transatlantic scientific organiser team of Nadja V. Tarakina (MPIKG, Germany) and Lena F. Kourkoutis (Cornell University, USA) have put together an exciting two-day programme. As usual, the first day will be more general, covering a broad range of microscopy approaches (correlative microscopy solutions, in-situ gas and liquid microscopy methods, low-voltage electron microscopy and many more) in the context of imaging hybrid and soft matter.

On the second day, the special Focus Lecture Series will provide an in-depth view on "Advances in Analytical Cryo-Electron Microscopy: From sample preparation to data acquisition to data analysis”. Cryo-electron microscopy has transformed life sciences by enabling the structure of macromolecules to be imaged down to the atomic scale. Recent developments in instrumentation and techniques have opened new opportunities for scientific discovery not only in life sciences but also in physical sciences and in areas where the two fields intersect. This lecture series will bring together world-leading experts in analytical electron microscopy, highlighting the latest achievements, new opportunities and outstanding challenges in probing beam-sensitive and hybrid materials and their interfaces.Â

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The Symposium will take place on Friday, 21st January 2022 at EBML, Heidelberg, and will bring together the User Community of the EMBL Cryo-EM Platform.
 

This is a one-day event with EMBL Cryo-EM Platform users presenting their results. In addition, there will be a session on new technologies for cryo-EM grid preparation. 

Invited speakers include Irina Gutsche (IBS Grenoble, FR), Arjen Jakobi (TU Delft, NL), Matthew Kraushar (MPI for Molecular Genetics, Berlin, DE), Daniel Levy (Institut Curie, Paris, FR), Melanie McDowell (MPI of Biophysics, Frankfurt, DE), Nathan Nelson (Tel Aviv University, IL), Gergely Papp (EMBL Grenoble, FR), Celia Plisson-Chastang (CBI Toulouse, FR), Miriam Weckener (RFI Didcot, UK), Michael Webster (John Innes Centre, Norwich, UK) and Giulia Zanetti (ISMB London, UK).
 
 

 

The participation and on-site catering is free of charge. 

The registration is open until 31st December 2021.

We aim to organise the Symposium as a physical, on-site event. All participants must comply with the German "2G rule" (being fully immunised against Coronavirus). We will require a proof of either vaccination or recent recovery from the infection. In addition, all participants are highly encouraged to make an antigen self-test before coming to the campus.
As per the government of Baden-Wuerttemberg regulations, please respect all hygiene measures and precautions like wearing a face mask in all circulation areas and observing the distance rule of 1.5m.