Stanford-SLAC CryoEM Center (S2C2) will offer a specimen preparation and data collection workshop via Zoom webinar between March 3-4, 2021 from 8:00 AM to approximately 1:00 PM (PST) daily. This workshop will give participants an introduction to cryo-specimen preparation approaches. Our guest lecturers include:

* Prof. Peter J. Peters, Maastricht Multimodal Molecular Imaging Institute (M4i), Maastricht University and CryoSol-World, Netherlands

* Dr. Benjamin Bammes, Direct Electron, LP

* Dr. Jeff Lengyel, Thermo Fisher

* Dr. Christopher Russo, LMB, MRC, Cambridge, UK

* Dr. Sahil Gulati, Ametek

* Dr. Yee L. Ting, SLAC National Accelerator Lab

* Dr. Patrick Mitchell, SLAC National Accelerator Lab

There is no cost for this workshop.

Sci-ROI (Science and Research Opportunities in India), a U.S. based non-profit organization, is organizing a
?Cryo-electron microscopy in India? webinar on *December 5 (Saturday) at 8PM IST/9.30 AM EST/2.30 PM GST.*

The meeting has been organised by the UK EM Validation Network to present current thinking on cryo-EM map and map/model validation, and to consider future research directions that anticipate the growing needs in this area. The community effort to apply cryo-EM to structural proteins of SARS-CoV-2 has been a success story but has also highlighted the importance of structure validation.

Gerard Kleywegt (EMBL-EBI)

Garib Murshudov (MRC-LMB)

Elena Orlova (Birkbeck College)

Ardan Patwardhan (EMBL-EBI)

Alan Roseman (University of Manchester)

Peter B. Rosenthal (The Francis Crick Institute)

Maya Topf (Birkbeck College)

Martyn Winn (STFC)

The day will begin at 9am and will feature short talks by post-docs and graduate students, a poster session, a self-care power hour, a cryo-EM art contest judged by Prof. David Goodsell (Scripps Research,) a Keynote Panel about the future directions of cryo-EM, cryo-ET, and microED by Professor Rebecca Voorhees (Caltech), Dr. Danielle Grotjahn (Scripps Research), and Dr. Jessica Bruhn (Nanoimaging Services), and it will end with a virtual Happy Hour for all interested members of the community.

This conference will bring together experts and early stage researchers from the separate fields

• to provide a platform for structural biology within the cellular context
• to stimulate discussions about how to meaningfully integrate data from different methods
• to define what types of biological questions can already be addressed using in situ structural biology and which might be approached in the future

Session Topics

• Imaging across scales
• Structural analysis in situ
• Molecular sociology
• Biophysical analysis in cells
• Integrative modelling

The Phenix developers will be holding an online Phenix User Workshop on the 15th and 16th of September at 8am-12pm PDT. These times will work best for researchers in North and South America, Europe and Africa. We plan to hold a future workshop at a time better suited to researchers in Asia and Australasia.

The format of the workshop will be demos of the use of Phenix programs combined with slides to explain the theory. We expect an interactive meeting where attendees can ask questions for the Phenix team to answer.

The workshop will cover aspects of crystallography and cryo-EM in Phenix, with the final emphasis based on the applicants? research interests. To apply, send email to workshops@phenix-online.org with a short paragraph about your interests. We will make every effort to accommodate all applicants, but may need to defer some requests to a future workshop if demand is high. We are hoping this workshop will be a success, in which case we plan to host more in the future.

Confirmed speakers for the online version of the meeting include:

Chris Russo (MRC-LMB)
Joe Atherton (KCL)
Rouslan Efremov (VIB-VUB Center for Structural Biology)
Vicki Gold (University of Exeter)
Alex Noble (NYSBC)
Dimitry Tegunov (Max Planck Institute for Biophysical Chemistry)
Hongyi Xu (Stockholm University)

The meeting will hosted via Zoom and is free of charge but you will need to pre-register here:

https://urldefense.com/v3/__https://ukri.zoom.us/webinar/register/WN_7ZSLh1xWQcqjqtIE_I2Sjg__;!!Mih3wA!VS11IblTAvJKtc_iwtCmi_cPBxVv-FsDOKUVtND2saJ6WVC6pMO_K8b37Tf5datoVw$

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Crete 2020 - 1st International CryoEM Symposium/Workshop to be held at the University of Crete

 A series of morning lectures will cover fundamental aspects of cryoEM, SPA, tomography, image processing and molecular modelling. Afternoon hands-on sessions will provide practical experience on single particle analysis and sub-tomogram averaging with special emphasis on evaluation of results and model building into high and low resolution cryo-EM maps. Trainees will work together with instructors and have an in-depth hands-on opportunity to learn how to use the software packages SPHIRE (single particle), pyTOM (subtomogram averaging) and the modelling packages PHENIX, COOT, REFMAC (modelling and refinement into cryoEM maps) and several other tools.
 On Day 1 we will additionally hold a symposium. Our invited speakers will highlight recent developments in the field and showcase outstanding recent applications. Participants will have the opportunity to present their own work in a poster session and five poster presenters will be selected for a short talk.

Confirmed Speakers/Instructors
Werner Koehlbrandt/ MPI Biophysics, Frankfurt 'EMBO Keynote Lecture'
Susan Lea/ University of Oxford
Stefan Raunser/ MPI Mol. Physiology, Dortmund
Pavel Afonine/ UC Berkeley
Ariane Briegel/ Leiden University
Friedrich F?rster/ Utrecht University
Robert Nicholls/ MRC Cambridge
Joergen Plitzko/ MPI Biochemistry, Martinsried
Evangelia Chrysina/ NHRF Athens
Nektarios Tavernarakis/ IMBB-FORTH
Registration deadlines for the event are 30.04 (early bird) and 07.06 (final deadline). The registration fees include single room accommodation, breakfast, lunch, coffee breaks, local transport and some social events (travel has to be arranged separately).

13TH MARCH 2020: Note on the Coronavirus situation: A prediction about a possible influence of Corona on our event in ~7 months is of course not possible at the moment. The situation will be evaluated few months before the event and if necessary (hopefully not) the course will be postponed; slots will be reserved for successfully registered participants.

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This hands-on workshop is targeted to members of the cryo-EM community who
are learning how to process data. To this end, we have designed this
workshop to help participants who will bring their own data and have begun
data analysis. Each participant will be given a dedicated machine on Amazon
Web Services where they will be able to run RELION, cisTEM, cryoSPARC, and
Phenix. We are excited that developers and expert users of cryo-EM software
programs will be present to go through basic and advanced analysis for
cryo-EM structure determination, and are accessible for asking questions
during the workshop.

 *Instructors:*
Dr. Michael Cianfrocco, University of Michigan
Dr. Melanie Ohi, University of Michigan

*Lecturers:*
RELION - Dr. Xiaochen Bai (UT Southwestern)
cisTEM - Dr. Tim Grant (UW Madison)
cryoSPARC - Dr. Ali Punjani (University of Toronto)
Phenix - Dr. Paul Adams (UC Berkeley) & Dr. Pavel Afonine (UC Berkeley)

*Invited presenters: *
Dr. Elizabeth Kellogg (Cornell University)
Dr. Melody Campbell (UCSF)
Dr. Christopher Barnes (Caltech)
Dr. Jennifer Cash (University of Michigan)

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The workshop will be run from 9am-5pm at NCCAT and NRAMM, which is located at the New York Structural Biology Center in NYC. Lunch will be served.

This workshop is offered at NO COST, but limited to 20 attendees.

Developing the Synergy between Biophysics and Medicinal Chemistry to Deliver Better Drugs

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• Session 1 : Induced-proximity Drug Discovery : Selective Protein Degraders, PPI Stabilizers...
• Session 2 : Advances in Cryo-EM : Micro-ED, Sample Optimization and Grid Preparation
• Session 3 : Covalent Modifications for Drug Discovery
• Session 4 : Integrative Structural Biology & Biophysics - Including Computational Methods and Hybrid Methods
• Session 5 : Advances in Biophysical Techniques : Single-Molecule Techniques, Label-free Technologies, Surface-Immobilized Techniques beyond SPR...
• Session 6 : Hot Topics

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The conference aims to provide a forum to highlight state of the art developments in computational cryoEM and related themes as well as showcasing outstanding recent biological applications.

Topics include instrument technology, sample preparation, image processing, single particle reconstruction, tomography and model building. The schedule will also include the Diamond Light Source biological cryo-imaging user meeting for eBIC & B24.

Stanford-SLAC CryoEM Center (S²C²) will offer a training workshop held at SLAC National Accelerator Laboratory between January 15 and 17, 2020. This workshop covers the basic principles and practical protocols to obtain atomic models based on cryo-EM density maps at near atomic resolution. This workshop will consist of three days of lectures and hands-on training sessions.Â